Jason Mathews graduated from Bridge City High School in 1989, where he lettered in football, basketball, and track. He also earned the Eagle Scout Award as a freshman and All-District honors as a two-way lineman.
 
Mathews lettered three years at Texas A&M after attending Brigham Young as a defensive lineman for one year. He started at right tackle as a junior and senior at A&M, then was drafted by the Indianapolis Colts during his senior year in the third round of the 1994 NFL Draft.
 
During his first year as an Indianapolis Colt, he played in 10 games as a reserve right tackle and on special teams. In the following year, he started all 16 games at right tackle and started in three playoff games as the Colts advanced to the 1995 AFC Championship game. In his third year with the Colts, Mathews played both right and left tackle. In 1997 he played 16 games as a reserve tackle and on special teams.
 
Mathews signed as a free agent with the Tennessee Oilers on September 1, 1998, and the team became the Tennessee Titans in 1999. After an incredible playoff run, Jason earned an AFC Championship ring with a win over the Jacksonville Jaguars. Titans represented the AFC in Super Bowl XXXIV, but were unable to secure the win against the St. Louis Rams. He played with the Tennessee Titans until retiring in 2004.